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NIA Seminar by Nancy Xu |
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Date: March 31, 2006
Time: 10:30am
Location: NIA, Rm 137
Design of Single Nanoparticle Optics for Probing Living Cellular Function
X. Nancy Xu, Old Dominion University
Membrane proteins in living cells can specifically recognize an array of structurally unrelated chemotoxics and assemble membrane transporters (efflux pump) optimized for extruding them selectively out of the cells. These smart sensing and transport mechanisms occur at the nanoscale regime. Using single nanoparticle optics, the Xu group has demonstrated real-time sizing of single nanoparticle transport in and out of living cells.
In this seminar, we will describe the design of biocompatible nanoparticles for probing such fascinating sensing and transport mechanisms in single living cells in real-time. This study will lead to new knowledge that is essential to better understanding of nanoparticle optics, the future design and assembly of biologically inspired smart molecular pumps and sensors, and the potential impacts of nanomaterials on our environment. Such new knowledge will advance our understanding of an array of research topics in biology, chemistry, environment, material science and engineering.
The work is supported by NSF.
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